Draft Genome Sequence of Mycobacterium bovis Strain AN5, Used for Production of Purified Protein Derivative

نویسندگان

  • Ana Beatriz Canevari Castelão
  • Christiane Nishibe
  • André Moura
  • Andrea Padilha de Alencar
  • Mariana de Azevedo Issa
  • Mikael Arrais Hodon
  • Pedro Moacyr Pinto Coelho Mota
  • Érica Bravo Sales
  • Antônio Augusto Fonseca Júnior
  • Nalvo Franco Almeida
  • Flábio Ribeiro Araújo
چکیده

Mycobacterium bovis strain AN5 has been used to produce purified protein derivative (PPD) for the intradermal test for bovine tuberculosis since it was introduced in 1948. This work reports the draft genome sequence of M. bovis AN5, which is used for the production of bovine PPD in Brazil, as well as comparisons to other strains of M. bovis and Mycobacterium tuberculosis.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Production of MPT-64 recombinant protein from virulent strain of Mycobacterium bovis

Tuberculosis (TB) is a zoonotic infectious disease common to humans and animals which has been caused by a rod shaped, acid fast bacterium, called Mycobacterium bovis. The rapid and sensitive detection is a great challenge for TB diagnosis. The virulent strains of Mycobacterium tuberculosis complex (MTBC) have 16 different regions of difference (RD) in their genome which encode some important a...

متن کامل

Assessment of a PPD tuberculin produced from the BCG strain of Mycobacterium bovis for use in cattle

The possibility of using BCG — a Mycobacterium bovis strain of attenuated virulence for PPD production instead of a virulent strain of M. bovis has been considered to avoid the biological risks involved in the procedure. The potency and specificity of a PPD tuberculin prepared from BCG was compared in guinea pigs with that of PPD produced from strain AN5 (two batches), a virulent strain of M. b...

متن کامل

Draft Genome Sequence of Mycobacterium bovis Strain D-10-02315 Isolated from Wild Boar

Mycobacterium bovis is the etiologic agent of bovine tuberculosis, a chronic infectious disease, affecting livestock, wild animals, and sometimes humans. We report the draft genome sequence of a Mycobacterium bovis strain isolated from wild boar of spoligotype SB0120 (or BCG-like) also present in wildlife-livestock multi-host systems.

متن کامل

Draft Genome Sequence of the Vaccination Strain Mycobacterium bovis BCG S4-Jena

Here, we present the draft genome sequence of ITALIC! Mycobacterium bovisBCG S4-Jena, a tuberculosis vaccine strain. The genome of S4-Jena is represented by 48 scaffolds, consisting of 132 scaffolded contigs and amounting to a size of about 4.2 Mb. New genes potentially encoding a phage fragment were identified in the genome.

متن کامل

First Whole-Genome Sequence of a Clinical Isolate of Multidrug-Resistant Mycobacterium bovis BCG

The attenuated BCG strain of Mycobacterium bovis is widely used as a vaccine against tuberculosis. However, in rare cases, it can be pathogenic to humans. Here, we report the first draft of a whole-genome sequence of a multidrug-resistant clinical isolate of M. bovis BCG.

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره 2  شماره 

صفحات  -

تاریخ انتشار 2014